Invention Grant
US09409975B2 Antibody binding microbial heparin binding motif to retard or prevent microbial biofilm formation on implanted medical devices
有权
抗体结合微生物肝素结合基序以延缓或预防植入的医疗设备上的微生物生物膜形成
- Patent Title: Antibody binding microbial heparin binding motif to retard or prevent microbial biofilm formation on implanted medical devices
- Patent Title (中): 抗体结合微生物肝素结合基序以延缓或预防植入的医疗设备上的微生物生物膜形成
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Application No.: US14518051Application Date: 2014-10-20
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Publication No.: US09409975B2Publication Date: 2016-08-09
- Inventor: Margaret K. Hostetter , Long Lu , Julianne Vernadette Green , Alexey Porollo , Kris I. Orsborn , Khoon Ghee Queenie Tan , Kenneth Greis , David Andes
- Applicant: Margaret K. Hostetter , Long Lu , Julianne Vernadette Green , Alexey Porollo , Kris I. Orsborn , Khoon Ghee Queenie Tan , Kenneth Greis , David Andes
- Applicant Address: US OH Cincinnati US OH Cincinnati US CT New Haven
- Assignee: Children's Hospital Medical Center,University of Cincinnati,Yale University
- Current Assignee: Children's Hospital Medical Center,University of Cincinnati,Yale University
- Current Assignee Address: US OH Cincinnati US OH Cincinnati US CT New Haven
- Agency: Thompson Hine LLP
- Main IPC: A61K31/00
- IPC: A61K31/00 ; A61K39/395 ; C07K16/00 ; C07K16/14 ; C07K16/12 ; C07K7/08 ; A61K39/00
Abstract:
Methods and reagents for ameliorating biofilm formation on a surface of an indwelling or implanted device in a patient resulting in decreased virulence of microorganisms such as Candida species and/or Staphylococcus species.
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