Invention Grant
US09409987B2 Polypeptides and polynucleotides, and uses thereof for treatment of immune related disorders and cancer
有权
多肽和多核苷酸,及其用于治疗免疫相关疾病和癌症的用途
- Patent Title: Polypeptides and polynucleotides, and uses thereof for treatment of immune related disorders and cancer
- Patent Title (中): 多肽和多核苷酸,及其用于治疗免疫相关疾病和癌症的用途
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Application No.: US14111767Application Date: 2012-04-16
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Publication No.: US09409987B2Publication Date: 2016-08-09
- Inventor: Amir Toporik , Amit Novik , Ronen Shemesh
- Applicant: Amir Toporik , Amit Novik , Ronen Shemesh
- Applicant Address: IL Holon
- Assignee: COMPUGEN LTD
- Current Assignee: COMPUGEN LTD
- Current Assignee Address: IL Holon
- Agency: Graeser Associates International Inc
- Agent Dvorah Graeser
- International Application: PCT/IB2012/051868 WO 20120416
- International Announcement: WO2012/140627 WO 20121018
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/395 ; A61K39/00 ; A61K39/39 ; C07K14/705 ; C07K16/18 ; G01N33/53

Abstract:
This invention relates to LY6G6F, VSIG10, TMEM25 and LSR proteins, which are suitable targets for immunotherapy, treatment of cancer, infectious disorders, and/or immune related disorders, and drug development. This invention further relates to soluble LY6G6F, VSIG10, TMEM25 and LSR molecules, extracellular domains of LY6G6F, VSIG10, TMEM25 and LSR and conjugates, which are suitable drugs for immunotherapy, treatment of cancer, infectious disorders, and/or immune related disorders. This invention further relates to antibodies and antigen binding fragments and conjugates containing same, and/or alternative scaffolds, specific for LY6G6F, VSIG10, TMEM25 or LSR molecules, which are suitable drugs for immunotherapy, treatment of cancer, infectious disorders, and/or immune related disorders.
Public/Granted literature
- US20140044641A1 POLYPEPTIDES AND POLYNUCLEOTIDES, AND USES THEREOF FOR TREATMENT OF IMMUNE RELATED DISORDERS AND CANCER Public/Granted day:2014-02-13
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