Invention Grant
- Patent Title: Method for determining and treating amyotrophic lateral sclerosis
- Patent Title (中): 确定和治疗肌萎缩性侧索硬化症的方法
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Application No.: US14854051Application Date: 2015-09-15
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Publication No.: US09410969B2Publication Date: 2016-08-09
- Inventor: Hao-Teng Chang , Margaret Dah-Tsyr Chang , Chi-Shin Hwang
- Applicant: National Tsing Hua University , China Medical University
- Applicant Address: TW Hsinchu TW Taichung
- Assignee: National Tsing Hua University,China Medical University
- Current Assignee: National Tsing Hua University,China Medical University
- Current Assignee Address: TW Hsinchu TW Taichung
- Agent Hannah M. Tien
- Main IPC: C07K16/34
- IPC: C07K16/34 ; A61P25/28 ; G01N33/68 ; A61K31/428 ; C07K16/18 ; G01N33/564
Abstract:
The present invention provides a method of determining and treating amyotrophic lateral sclerosis (ALS) in a subject, comprising the following steps: (1) measuring a concentration of an autoantibody against high mobility group box 1 protein (HMGB1) in a biological sample from the subject; and (2) administering an effective amount of ALS-treating drug to the subject whose measured concentration of the autoantibody against HMGB1 is higher than 0.874 μg/ml.
Public/Granted literature
- US20150377912A1 Method for Determining and Treating Amyotrophic Lateral Sclerosis Public/Granted day:2015-12-31
Information query
