The storage processor of a data storage system such as a storage array automatically configures one or more accelerator caches (“AC”) upon detecting the presence of one or more solid-state storage devices (e.g., SSD drives) installed in the data storage system, such as when a storage device is plugged into a designated slot of the data storage system, without requiring any user configuration of the AC or specification by the user of the type(s) of data to be cached in the AC. The AC therefore provides a zero configuration cache that can be used to cache any of various types of data in the data storage system. The AC cache can be used in any of a wide variety of data storage systems including, without limitation, file servers, storage arrays, computers, etc. Multiple ACs may be created to cache different types of data.