Embodiments of a multi-radio controller and methods for preventing interference between co-located transceivers are generally described herein. In some embodiments, the multi-radio controller operates within a multi-radio device and is configured to cause a wireless local area network (WLAN) transceiver to transmit a triggering frame after an active period of a wireless wide-area network (WWAN) transceiver. The triggering frame indicates the duration of a transmission opportunity, which may be restricted to the time between active periods of the WWAN. In response to receipt of the triggering frame, the WLAN access point is configured to transmit a downlink data frame within the transmission opportunity.