Invention Grant
- Patent Title: Conjugates of a polymer, a bisphosphonate and an anti-angiogenesis agent and uses thereof in the treatment and monitoring of bone related diseases
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Application No.: US14816228Application Date: 2015-08-03
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Publication No.: US09427474B2Publication Date: 2016-08-30
- Inventor: Ronit Satchi-Fainaro , Keren Miller , Doron Shabat , Rotem Erez
- Applicant: Ramot at Tel-Aviv University Ltd.
- Applicant Address: IL Tel-Aviv
- Assignee: Ramot at Tel-Aviv University Ltd.
- Current Assignee: Ramot at Tel-Aviv University Ltd.
- Current Assignee Address: IL Tel-Aviv
- Main IPC: A61K31/74
- IPC: A61K31/74 ; A61K47/48 ; A61K49/00 ; C07F9/38 ; C07F9/655 ; C07F9/6558 ; C07K5/065 ; C07K5/103 ; A61K31/337 ; A61K9/16
Abstract:
Conjugates of polymers or copolymers having attached thereto an anti-angiogenesis agent and a bisphosphonate bone targeting agent, and processes of preparing same, are disclosed.Pharmaceutical compositions containing these conjugates and uses thereof in the treatment of bone related disorders are also disclosed.
Public/Granted literature
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