Invention Grant
US09428511B2 Imidazopyridazine JAK3 inhibitors and their use for the treatment of inflammatory and autoimmune diseases
有权
咪唑并哒嗪JAK3抑制剂及其用于治疗炎症和自身免疫性疾病的用途
- Patent Title: Imidazopyridazine JAK3 inhibitors and their use for the treatment of inflammatory and autoimmune diseases
- Patent Title (中): 咪唑并哒嗪JAK3抑制剂及其用于治疗炎症和自身免疫性疾病的用途
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Application No.: US14426625Application Date: 2013-09-05
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Publication No.: US09428511B2Publication Date: 2016-08-30
- Inventor: Bingwei Vera Yang , Gregory D. Brown , Arun Kumar Gupta , William J. Pitts
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Mary VanAtten
- International Application: PCT/US2013/058114 WO 20130905
- International Announcement: WO2014/039595 WO 20140313
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07B59/00
Abstract:
The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of JAK3, thereby making them useful for the treatment of inflammatory and autoimmune diseases.
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