Invention Grant
- Patent Title: Piperazines, pharmaceutical compositions and methods of use thereof
- Patent Title (中): 哌嗪，药物组合物及其使用方法
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Application No.: US14445458Application Date: 2014-07-29
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Publication No.: US09428522B2Publication Date: 2016-08-30
- Inventor: Roger B. Clark , Daniel Elbaum
- Applicant: CORNERSTONE THERAPEUTICS, INC.
- Applicant Address: US NY Manhasset
- Assignee: The Feinstein Institute for Medical Research
- Current Assignee: The Feinstein Institute for Medical Research
- Current Assignee Address: US NY Manhasset
- Agency: Saul Ewing LLP
- Agent Kathryn Doyle; Domingos J. Silva
- Main IPC: A61K31/497
- IPC: A61K31/497 ; A61K31/535 ; C07D401/12 ; C07D513/04 ; C07D498/04 ; C07D405/14 ; C07D413/14 ; C07D409/14 ; C07D417/14 ; C07D241/04 ; C07D401/14 ; C07D513/14
Abstract:
Disclosed are novel piperazine derivatives that act as agonists of the α7 nAChR. Also disclosed are pharmaceutical compositions, methods of treating inflammatory conditions, methods of treating CNS disorders, methods for inhibiting cytokine release from mammalian cells and methods for the preparation of the novel compounds.
Public/Granted literature
- US20140343059A1 NOVEL PIPERAZINES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF Public/Granted day:2014-11-20
Information query
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