Invention Grant
US09428753B2 Use of LXR antagonists for treatment of side effects of elevated glucocorticoid levels
有权
使用LXR拮抗剂治疗糖皮质激素水平升高的副作用
- Patent Title: Use of LXR antagonists for treatment of side effects of elevated glucocorticoid levels
- Patent Title (中): 使用LXR拮抗剂治疗糖皮质激素水平升高的副作用
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Application No.: US14178384Application Date: 2014-02-12
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Publication No.: US09428753B2Publication Date: 2016-08-30
- Inventor: Carolyn Cummins , Arturo Orellana , Rucha Patel , Fernando A. Fernandez
- Applicant: The Governing Council of the University of Toronto , Fernado A. Fernandez , Arturo Orellana
- Applicant Address: CA Toronto CA Etobicoke CA Toronto
- Assignee: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO,Fernando A. Fernandez,Arturo Orellana
- Current Assignee: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO,Fernando A. Fernandez,Arturo Orellana
- Current Assignee Address: CA Toronto CA Etobicoke CA Toronto
- Agency: Bereskin & Parr LLP/S.E.N.C.R.L., s.r.l.
- Agent Patricia Folkins
- Priority: CA2819448 20130621
- Main IPC: A61K31/341
- IPC: A61K31/341 ; A61K31/18 ; A61K31/573 ; C07J41/00 ; C12N15/113

Abstract:
The present application is directed to uses of an agent that antagonizes the LXRβ receptor for the treatment of side effects associated with elevated glucocorticoid levels as well as uses of a glucocorticoid in combination with the agent that antagonizes the LXRβ receptor for treatment of a disease wherein glucocorticoid treatment is indicated.
Public/Granted literature
- US20140271673A1 USE OF LXR ANTAGONISTS FOR TREATMENT OF SIDE EFFECTS OF ELEVATED GLUCOCORTICOID LEVELS Public/Granted day:2014-09-18
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