Invention Grant
- Patent Title: Method for prevention and treatment of Escherichia coli infections using a bacteriophage with broad antibacterial spectrum against Escherichia coli
- Patent Title (中): 使用广谱抗菌谱对大肠杆菌的噬菌体预防和治疗大肠杆菌感染的方法
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Application No.: US14706325Application Date: 2015-05-07
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Publication No.: US09433653B2Publication Date: 2016-09-06
- Inventor: Seong Jun Yoon , Soo Youn Jun , Hyoung Rok Paik , Jee Soo Son , Hye In Jeong , Sang Hyeon Kang
- Applicant: iNtRON Biotechnology, Inc.
- Applicant Address: KR Kyeonggi-Do
- Assignee: INTRON BIOTECHNOLOGY, INC.
- Current Assignee: INTRON BIOTECHNOLOGY, INC.
- Current Assignee Address: KR Kyeonggi-Do
- Agency: Pearl Cohen Zedek Latzer Baratz LLP
- Priority: KR10-2014-0053909 20140507
- Main IPC: C12N7/00
- IPC: C12N7/00 ; A61K35/76
Abstract:
The present invention relates to a composition comprising the bacteriophage EK88P-1 isolated from the nature and having a broad antibacterial spectrum against E. coli as an active ingredient, and a method for preventing and treating E. coli infections using the said composition. The bacteriophage EK88P-1, the active ingredient of the composition of the present invention, has a broad antibacterial spectrum against E. coli and has the genome characteristically composed of the partial nucleotide sequences represented by SEQ ID NO: 1 to SEQ ID NO: 25, and also characterized by the bacteriophage belonging to the Myoviridae family according to the morphology that is composed of the major structural proteins in the sizes of approximately 49 kDa, 53 kDa, 94 kDa, and 103 kDa.
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