Invention Grant
- Patent Title: Combination therapy involving antibodies against claudin 18.2 for treatment of cancer
- Patent Title (中): 联合治疗涉及克劳丁18.2抗体治疗癌症
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Application No.: US14401557Application Date: 2013-05-21
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Publication No.: US09433675B2Publication Date: 2016-09-06
- Inventor: Ugur Sahin , Özlem Türeci , Rita Mitnacht-Kraus , Stefan Denis Jacobs , Magdalena Jadwiga Utsch , Cornelia Adriana Maria Heinz , Christiane Regina Stadler
- Applicant: GANYMED PHARMACEUTICALS AG , TRON—Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg-Universität Mainz gemeinnützige GmbH
- Applicant Address: DE Mainz DE Mainz
- Assignee: Ganymed Pharmaceuticals AG,TRON—Translationale Onkologie an der Universitatsmedizin der Johannes Gutenberg-Universitat Mainz Gemeinnutzige GmbH
- Current Assignee: Ganymed Pharmaceuticals AG,TRON—Translationale Onkologie an der Universitatsmedizin der Johannes Gutenberg-Universitat Mainz Gemeinnutzige GmbH
- Current Assignee Address: DE Mainz DE Mainz
- Agency: Neal, Gerber & Eisenberg LLP
- Priority: EPPCT/EP2012/002211 20120523
- International Application: PCT/EP2013/001503 WO 20130521
- International Announcement: WO2013/174509 WO 20131128
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K39/00 ; A01N57/00 ; A01N33/02 ; A01N43/40 ; A61K45/06 ; C07K16/30 ; A61K31/282 ; A61K31/337 ; A61K31/4375 ; A61K31/513 ; A61K31/519 ; A61K31/675 ; A61K31/704 ; A61K33/24 ; A61K38/20
Abstract:
The present invention provides a combination therapy for effectively treating and/or preventing diseases associated with cells expressing CLDN18.2, including cancer diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder and metastases thereof.
Public/Granted literature
- US20150157711A1 COMBINATION THERAPY INVOLVING ANTIBODIES AGAINST CLAUDIN 18.2 FOR TREATMENT OF CANCER Public/Granted day:2015-06-11
Information query
