The disclosure relates to a method of manufacturing a heat exchanger assembly with an enhanced material system. The enhanced material system includes refrigerant tubes extruded from a high purity AA3000 series alloy billet having about 1% by weight (wt %) Mn and pre-braze treated with either a reactive zinc flux or a mixture of elemental zinc powder and a controlled atmosphere brazed (CAB) flux applied by glass plasma or organic binder, such as an organic binder, fins formed from modified a AA3003 alloy having less than 0.05 wt % Cu and from 1.2 to 1.8% wt % Zn, and header manifolds manufactured from a AA3000 series alloy with a AA4000 series cladding having 0.9 to 1.1 wt % Zn. The enhanced material system may also include a post braze coating and a subsequent organic polymer resin topcoat.