Invention Grant
US09434701B2 Aminoquinoxaline derivatives for treatment of neurodegenerative diseases
有权
用于治疗神经变性疾病的氨基喹喔啉衍生物
- Patent Title: Aminoquinoxaline derivatives for treatment of neurodegenerative diseases
- Patent Title (中): 用于治疗神经变性疾病的氨基喹喔啉衍生物
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Application No.: US14008189Application Date: 2012-03-30
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Publication No.: US09434701B2Publication Date: 2016-09-06
- Inventor: Laurent Ferrie , Bruno Figadere , Gaël Le Douaron , Rita Raisman-Vozari , Fanny Schmidt
- Applicant: Laurent Ferrie , Bruno Figadere , Gaël Le Douaron , Rita Raisman-Vozari , Fanny Schmidt
- Applicant Address: FR Paris FR Orsay
- Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS),UNIVERSITE PARIS—SUD 11
- Current Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS),UNIVERSITE PARIS—SUD 11
- Current Assignee Address: FR Paris FR Orsay
- Agency: Foley & Lardner LLP
- Priority: FR1152645 20110330
- International Application: PCT/EP2012/055903 WO 20120330
- International Announcement: WO2012/131080 WO 20121004
- Main IPC: A61K31/498
- IPC: A61K31/498 ; C07D241/42

Abstract:
The present invention relates to compounds of formula (I) below: for which: —X represents a hydrogen atom, a halogen atom, a group NO2 or NH2, —R0 represents H or —CH2—C≡CH, and —R1 and R2 each represent, independently of one another, a hydrogen atom; a saturated or unsaturated, linear or branched hydrocarbon-based chain comprising from 1 to 10 carbon atoms; or an optionally substituted aryl group, and also the pharmaceutically acceptable salts thereof, the stereoisomers thereof or mixtures of stereoisomers thereof in any proportion, in particular for use thereof as a medicament, in particular in the treatment or prevention of neurodegenerative diseases, and also the processes for the preparation thereof and the pharmaceutical compositions comprising same.
Public/Granted literature
- US20140113903A1 AMINOQUINOXALINE DERIVATIVES FOR TREATMENT OF NEURODEGENERATIVE DISEASES Public/Granted day:2014-04-24
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