Invention Grant
US09434737B2 Process for producing optically active succinimide derivatives and intermediates thereof
有权
光学活性琥珀酰亚胺衍生物的制造方法及其中间体
- Patent Title: Process for producing optically active succinimide derivatives and intermediates thereof
- Patent Title (中): 光学活性琥珀酰亚胺衍生物的制造方法及其中间体
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Application No.: US14104597Application Date: 2013-12-12
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Publication No.: US09434737B2Publication Date: 2016-09-06
- Inventor: Masaji Kasai , Shinji Kita , Tadashi Ogawa , Hideaki Tokai
- Applicant: Dainippon Sumitomo Pharma Co., Ltd. , Kyowa Hakko Bio Co., Ltd.
- Applicant Address: JP Osaka JP Tokyo
- Assignee: Sumitomo Dainippon Pharma Co., Ltd.,Kyowa Hakko Bio Co., Ltd.
- Current Assignee: Sumitomo Dainippon Pharma Co., Ltd.,Kyowa Hakko Bio Co., Ltd.
- Current Assignee Address: JP Osaka JP Tokyo
- Agency: Leydig, Voit & Mayer, Ltd.
- Priority: JP2009-025599 20090206
- Main IPC: C07D487/20
- IPC: C07D487/20 ; C07C271/22 ; C07D207/416 ; C12P7/62 ; C12P17/10 ; C12P41/00 ; C12P17/18
Abstract:
Provided is a process for producing (3R)-2′-(4-bromo-2-fluorobenzyl)spiro{pyrrolidine-3,4′(1′H)-pyrrolo[1,2-a]pyrazine}-1′,2,3′,5(2′H)-tetraone (compound A). The method includes converting an optically active succinimide derivative of formula (I) to compound A, in which the compound of formula (I) has been prepared by reacting a base with an optically active amide derivative of formula (VI).
Public/Granted literature
- US20140099681A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE SUCCINIMIDE DERIVATIVES AND INTERMEDIATES THEREOF Public/Granted day:2014-04-10
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