Invention Grant
US09434763B2 Derivatives of pyridinone as inhibitors for tissue transglutaminase
有权
吡啶酮的衍生物作为组织转谷氨酰胺酶的抑制剂
- Patent Title: Derivatives of pyridinone as inhibitors for tissue transglutaminase
- Patent Title (中): 吡啶酮的衍生物作为组织转谷氨酰胺酶的抑制剂
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Application No.: US14415374Application Date: 2013-07-12
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Publication No.: US09434763B2Publication Date: 2016-09-06
- Inventor: Christian Buchold , Uwe Gerlach , Martin Hils , Ralf Pasternack , Johannes Weber
- Applicant: ZEDIRA GMBH
- Applicant Address: DE Darmstadt
- Assignee: ZEDIRA GMBH
- Current Assignee: ZEDIRA GMBH
- Current Assignee Address: DE Darmstadt
- Agency: Knobbe, Martens, Olson & Bear, LLP
- Priority: EP12176776 20120717
- International Application: PCT/EP2013/064789 WO 20130712
- International Announcement: WO2014/012858 WO 20140123
- Main IPC: A61K45/06
- IPC: A61K45/06 ; C07K5/093 ; A61K38/07 ; C07K1/06 ; C07K5/113 ; A61K38/06 ; C07K5/10 ; C07D213/75 ; C07D401/12 ; C07D405/12 ; C07D409/12 ; C07D413/12 ; C07D417/12 ; C07D493/10 ; C07D401/06 ; C07K5/02 ; C07K5/083 ; C07K5/117
Abstract:
The invention relates to pyridinone derivatives of general formula (I) as inhibitors of tissue transglutaminase, to methods for producing the pyridinone derivatives, to pharmaceutical compositions containing said pyridinone derivatives and to their use for the prophylaxis and treatment of diseases associated with tissue transglutaminase.
Public/Granted literature
- US20150203535A1 DERIVATIVES OF PYRIDINONE AS INHIBITORS FOR TISSUE TRANSGLUTAMINASE Public/Granted day:2015-07-23
Information query
