Invention Grant
US09434782B2 Animal models and therapeutic molecules 有权
动物模型和治疗分子

Animal models and therapeutic molecules
Abstract:
The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanized antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.
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