Invention Grant
- Patent Title: Combination therapy for treating hearing and balance disorders
- Patent Title (中): 用于治疗听力和平衡障碍的联合治疗
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Application No.: US14588955Application Date: 2015-01-04
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Publication No.: US09434946B2Publication Date: 2016-09-06
- Inventor: Svetlana Adamsky , Elena Feinstein
- Applicant: QUARK PHARMACEUTICALS, INC.
- Applicant Address: US CA Fremont
- Assignee: QUARK PHARMACEUTICALS, INC.
- Current Assignee: QUARK PHARMACEUTICALS, INC.
- Current Assignee Address: US CA Fremont
- Agency: Nutter McClennen & Fish LLP
- Agent Konstantin Linnik; Isaac A. Hubner
- Priority: WOPCT/US2012/049616 20120803
- Main IPC: C12N15/11
- IPC: C12N15/11 ; A61K48/00 ; C07H21/02 ; C07H21/04 ; C12N15/113
Abstract:
The present application relates to combinations of inhibitors directed at down-regulation of genes associated with hearing loss including HES1, HES5, HEY2, CDKN1B and NOTCH1, exhibiting a beneficial effect and useful in treating or attenuating hearing loss, treating balance impairment, promoting the replacement, regeneration, or protection of otic (sensory) hair cells of the inner ear, and or effecting hearing restoration/regeneration.
Public/Granted literature
- US20150126586A1 COMBINATION THERAPY FOR TREATING HEARING AND BALANCE DISORDERS Public/Granted day:2015-05-07
Information query
IPC分类:
