Invention Grant
- Patent Title: Virus-like particles for treatment of viral infections
- Patent Title (中): 用于治疗病毒感染的病毒样颗粒
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Application No.: US14249864Application Date: 2014-04-10
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Publication No.: US09434959B2Publication Date: 2016-09-06
- Inventor: Leslie Lobel , Guy Gubi
- Applicant: BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY
- Applicant Address: IL Beer Sheva
- Assignee: BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY
- Current Assignee: BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY
- Current Assignee Address: IL Beer Sheva
- Agency: Browdy and Neimark, PLLC
- Main IPC: A01N63/00
- IPC: A01N63/00 ; A61K38/00 ; A61K39/395 ; C07H21/04 ; C07K1/00 ; C12N15/86 ; A61K39/145 ; C07K14/005 ; C07K16/10 ; C12N7/00 ; A61K39/12 ; C12N7/02 ; C12N7/04 ; A61K39/00
Abstract:
The invention provides virus-like particles for treatment of viral infections based on the virus causing the infection. The virus-like particles comprise the virus recombinant proteins that form a capsid, recombinant virus membrane proteins attached to the capsid and vRNA packaged within said capsid. The vRNA is generated from a DNA sequence encoding a polypeptide capable of specifically binding to a constant region of a nonstructural protein of the virus that is essential for propagation of the virus.
Public/Granted literature
- US20140213640A1 VIRUS-LIKE PARTICLES FOR TREATMENT OF VIRAL INFECTIONS Public/Granted day:2014-07-31
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