Invention Grant
- Patent Title: Breast cancer biomarker signatures for invasiveness and prognosis
- Patent Title (中): 乳腺癌生物标志物的侵袭性和预后特征
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Application No.: US14483232Application Date: 2014-09-11
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Publication No.: US09434995B2Publication Date: 2016-09-06
- Inventor: Carlo M. Croce , Stefano Volinia
- Applicant: The Ohio State University
- Applicant Address: US OH Columbus
- Assignee: The Ohio State University
- Current Assignee: The Ohio State University
- Current Assignee Address: US OH Columbus
- Agency: MacMillan, Sobanski & Todd, LLC
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G06F17/30
Abstract:
MicroRNA profiles transition from normal breast to ductal carcinoma in situ and transition to invasive ductal carcinoma (IDC) and methods of use thereof are described. Methods of diagnosis and prognosis using microRNA signatures to differentiate invasive from in situ carcinoma are described. Also described is the use of microRNA expression for predicting overall survival and time to metastasis.
Public/Granted literature
- US20140378535A1 Breast Cancer Biomarker Signatures for Invasiveness and Prognosis Public/Granted day:2014-12-25
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