A disc brake for a commercial vehicle includes a brake caliper, which surrounds a brake disc and which is retained on a stationary brake carrier by way of guide bushings. The guide bushings are fastened to the brake carrier by screws and are arranged parallel to and at a distance from each other and form plain bearings. The brake caliper is retained in such a way that the brake caliper can be moved in a brake-application direction. The disc brake is designed in such a way that each guide bushing is wedged together with the associated screw.