Invention Grant
- Patent Title: Use of leucyl tRNA synthetase
- Patent Title (中): 使用亮氨酰tRNA合成酶
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Application No.: US14223188Application Date: 2014-03-24
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Publication No.: US09435807B2Publication Date: 2016-09-06
- Inventor: Sunghoon Kim , Jung Min Han
- Applicant: Medicinal Bioconvergence Research Center
- Applicant Address: KR Suwon-si
- Assignee: Medicinal Bioconvergence Research Center
- Current Assignee: Medicinal Bioconvergence Research Center
- Current Assignee Address: KR Suwon-si
- Agency: H.C. Park & Associates, PLC
- Priority: KR10-2011-0095893 20110922
- Main IPC: G01N33/573
- IPC: G01N33/573 ; G01N33/574 ; C12N15/113

Abstract:
Provided is a method of screening for agents for preventing or treating mTORC 1 mediated diseases by screening test agents to determine test agents that inhibit the binding ability of LRS to RagD, or RagD GTPases, and a method of reducing cell size as compared to the control group, including inhibiting the expression of intracellular LRS in the cells.
Public/Granted literature
- US20140249045A1 NOVEL USE OF LEUCYL TRNA SYNTHETASE Public/Granted day:2014-09-04
Information query
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