Invention Grant
- Patent Title: Fenofibrate formulation
- Patent Title (中): 非诺贝特配方
-
Application No.: US14390556Application Date: 2012-10-23
-
Publication No.: US09439860B2Publication Date: 2016-09-13
- Inventor: Sarat C. Chattaraj , Glenn Allen Redelman , Andrew Alan Shaw
- Applicant: MYLAN, INC.
- Applicant Address: US WV Morgantown
- Assignee: Mylan, Inc.
- Current Assignee: Mylan, Inc.
- Current Assignee Address: US WV Morgantown
- Agency: Kramer & Amado
- International Application: PCT/US2012/061486 WO 20121023
- International Announcement: WO2014/003810 WO 20140103
- Main IPC: A61K9/14
- IPC: A61K9/14 ; A61K9/50 ; A61K45/06 ; A61K31/216

Abstract:
Various fenofibrate dosage forms contain a plurality of beads or particles, where the beads or particles include a pharmaceutical composition comprising fenofibrate; from 0.3% to 10% by weight of the beads or particles of a surfactant; and from about 5% to about 15% by weight of the beads or particles of a water soluble or water dispersible cellulosic binder. The mass ratio of the drug to the binder in the dosage form is between about 3.5:1 and 4.5:1; and the dosage form produces a first Cmax in vivo that is between about 10% and about 50% higher than a comparative Cmax produced by a comparative dosage form. The comparative dosage form comprises the drug and the binder in a ratio of between about 5:1 and 15:1.
Public/Granted literature
- US20150118317A1 FENOFIBRATE FORMULATION Public/Granted day:2015-04-30
Information query