Invention Grant
US09439908B2 Cross-linking composition delivered by iontophoresis, useful for the treatment of keratoconus
有权
通过离子电渗法递送的交联组合物，可用于治疗圆锥角膜
- Patent Title: Cross-linking composition delivered by iontophoresis, useful for the treatment of keratoconus
- Patent Title (中): 通过离子电渗法递送的交联组合物，可用于治疗圆锥角膜
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Application No.: US14353872Application Date: 2012-10-24
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Publication No.: US09439908B2Publication Date: 2016-09-13
- Inventor: Fulvio Foschini , Marcello Stagni , Giulio Luciani , Pierre Roy
- Applicant: SOOFT ITALIA SPA
- Applicant Address: IT Montegiorgio (FM)
- Assignee: SOOFT ITALIA SPA
- Current Assignee: SOOFT ITALIA SPA
- Current Assignee Address: IT Montegiorgio (FM)
- Agency: Young & Thompson
- Priority: ITRM2011A0560 20111025
- International Application: PCT/IT2012/000324 WO 20121024
- International Announcement: WO2013/061350 WO 20130502
- Main IPC: A61K31/525
- IPC: A61K31/525 ; A61K9/00
Abstract:
An improved formulation of an ophthalmic composition contains riboflavin, as cross-linking agent of corneal collagen, administered by corneal iontophoresis, able to guarantee an increased capacity of permeation of riboflavin of the corneal stroma and therefore greater therapeutic efficacy in the treatment of keratoconus.
Public/Granted literature
- US20140303173A1 CROSS-LINKING COMPOSITION DELIVERED BY IONTOPHORESIS, USEFUL FOR THE TREATMENT OF KERATOCONUS Public/Granted day:2014-10-09
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