Invention Grant
US09439958B2 Stabilized virus like particles having enhanced mucosal immunogenicity
有权
具有增强的粘膜免疫原性的稳定的病毒样颗粒
- Patent Title: Stabilized virus like particles having enhanced mucosal immunogenicity
- Patent Title (中): 具有增强的粘膜免疫原性的稳定的病毒样颗粒
-
Application No.: US13518504Application Date: 2010-12-23
-
Publication No.: US09439958B2Publication Date: 2016-09-13
- Inventor: Charles J. Arntzen , Melissa Herbst-Kralovetz
- Applicant: Charles J. Arntzen , Melissa Herbst-Kralovetz
- Applicant Address: US AZ Scottsdale
- Assignee: ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
- Current Assignee: ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
- Current Assignee Address: US AZ Scottsdale
- Agency: Citadel Patent Law
- Agent George A. Leone
- International Application: PCT/US2010/061993 WO 20101223
- International Announcement: WO2011/079260 WO 20110630
- Main IPC: A61K39/12
- IPC: A61K39/12 ; C12N7/00 ; A61K9/00 ; A61K9/16 ; A61K39/125 ; A61K39/00

Abstract:
A method of producing an immune response in a subject including the step of administering to the subject a dry powder vaccine composition having a dry powder containing a subunit antigen with virus-like particles, where the subunit antigen is stabilized by a polysaccharide-containing plant extract, and where mucosal vaccination results in an immune response which is not further enhanced by co-inclusion of adjuvants.
Public/Granted literature
- US20130095134A1 STABILIZED VIRUS LIKE PARTICLES HAVING ENHANCED MUCOSAL IMMUNOGENICITY Public/Granted day:2013-04-18
Information query