Invention Grant
- Patent Title: Fluorescent cyanine-polyamine derivatives as a diagnostic probe
- Patent Title (中): 荧光花青多胺衍生物作为诊断探针
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Application No.: US13822535Application Date: 2011-11-24
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Publication No.: US09439982B2Publication Date: 2016-09-13
- Inventor: Yves Guminski , Thierry Imbert , Sabrina Pesnel , Arnaud Pillon , Alain Le Pape , Stephanie Lerondel
- Applicant: Yves Guminski , Thierry Imbert , Sabrina Pesnel , Arnaud Pillon , Alain Le Pape , Stephanie Lerondel
- Applicant Address: FR Boulogne-Billancourt FR Paris
- Assignee: PIERRE FABRE MEDICAMENT,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
- Current Assignee: PIERRE FABRE MEDICAMENT,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
- Current Assignee Address: FR Boulogne-Billancourt FR Paris
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: FR1059687 20101124
- International Application: PCT/EP2011/070980 WO 20111124
- International Announcement: WO2012/069607 WO 20120531
- Main IPC: A61B5/00
- IPC: A61B5/00 ; A61B8/00 ; A61B10/00 ; A61K49/00 ; C07D209/14 ; C07D403/06

Abstract:
The invention relates to fluorescent derivatives of cyanines conjugated with a polyamine group, having formula (I), or a pharmaceutically acceptable salt thereof. The invention also relates to the method for preparing said derivatives, diagnostic compositions containing same and the use thereof as a diagnostic probe for the detection of cancer tumors, in particular in vivo.
Public/Granted literature
- US20130183247A1 FLUORESCENT CYANINE-POLYAMINE DERIVATIVES AS A DIAGNOSTIC PROBE Public/Granted day:2013-07-18
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