Invention Grant
- Patent Title: Composite collagen sponge and preparation method thereof
- Patent Title (中): 复合胶原海绵及其制备方法
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Application No.: US14235355Application Date: 2012-06-07
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Publication No.: US09439999B2Publication Date: 2016-09-13
- Inventor: Shanshan Wang
- Applicant: Shanshan Wang
- Applicant Address: CN
- Assignee: Harbin Peiqilong Biopharmaceutical Co., Ltd
- Current Assignee: Harbin Peiqilong Biopharmaceutical Co., Ltd
- Current Assignee Address: CN
- Agency: Dilworth IP, LLC
- Priority: CN201110212713 20110728
- International Application: PCT/CN2012/076577 WO 20120607
- International Announcement: WO2013/013537 WO 20130131
- Main IPC: A61L15/32
- IPC: A61L15/32 ; A61L27/56 ; A61L27/24 ; A61K38/39 ; A61L24/00 ; A61L24/10 ; A61K38/00

Abstract:
The present invention discloses a composite collagen sponge and the preparation method thereof. The composite collagen sponge comprises collagen, cell growth factors, and a protecting agent, and has a water absorption capacity of more than 52 times. The preparation method includes a cation chromatographic purification step and a two-stage inactivation step consisting of organic solvent/detergent virus inactivation and dry heat virus inactivation. The composite collagen sponge obtained by the method of the present invention not only improves the safety and performance of the product in clinical applications, but also ensures the stability and the bioactivity throughout the effective life of the product.
Public/Granted literature
- US20140235539A1 Composite Collagen Sponge and Preparation Method Thereof Public/Granted day:2014-08-21
Information query
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