A vacuum lamination machine suitable for all generations is disclosed. The vacuum lamination machine includes a stage on which a transfer device, a positioning device, an adhesive application device, a turn-over device, and at least one vacuum lamination device are arranged. The stage has a size that is sufficiently large for all sizes of substrate. The transfer device includes a fork that is adjustable for spacing distance to suit for substrate sizes. The turn-over device includes sufficiently densely arranged vacuum suction pins to suit for substrate sizes. The positioning device includes a size identification system that identifies a rough location of a substrate on the stage and a mark position identification system that carries out precise alignment of the substrate.