Invention Grant
US09440981B2 Pyrrolo[2, 1-F] [1,2,4]triazine derivative and use thereof for treating tumors
有权
吡咯并[2,1-F] [1,2,4]三嗪衍生物及其用于治疗肿瘤的用途
![Pyrrolo[2, 1-F] [1,2,4]triazine derivative and use thereof for treating tumors](/docs/US/2016-09-13/US09440981B2/abs.jpg.600x600.jpg)
- Patent Title: Pyrrolo[2, 1-F] [1,2,4]triazine derivative and use thereof for treating tumors
- Patent Title (中): 吡咯并[2,1-F] [1,2,4]三嗪衍生物及其用于治疗肿瘤的用途
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Application No.: US14404217Application Date: 2013-05-17
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Publication No.: US09440981B2Publication Date: 2016-09-13
- Inventor: Xihan Wu , Minmin Yang , Qingning Shu , Chunrui Zhu
- Applicant: PHARMABLOCK (NANJING) R&D CO. LTD.
- Applicant Address: CN Nanjing
- Assignee: PHARMABLOCK (NANJING) R&D CO. LTD
- Current Assignee: PHARMABLOCK (NANJING) R&D CO. LTD
- Current Assignee Address: CN Nanjing
- Agency: Ladas & Parry LLP
- Priority: CN201210178854 20120601
- International Application: PCT/CN2013/075796 WO 20130517
- International Announcement: WO2013/178021 WO 20131205
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/5377 ; C07D519/00
![Pyrrolo[2, 1-F] [1,2,4]triazine derivative and use thereof for treating tumors](/abs-image/US/2016/09/13/US09440981B2/abs.jpg.150x150.jpg)
Abstract:
Disclosed are a pyrrolo[2,1-f][1,2,4]triazine derivative of Formula (I) and use thereof for treating tumors. The compound has remarkable antiproliferative activity for a variety of human tumor cell lines, and is useful for treating cancers, especially solid tumors such as gastric cancer, lung cancer, liver cancer, breast cancer, colon cancer, prostatic cancer, and oral cancer.
Public/Granted literature
- US20160115166A1 PYRROLO[2, 1-F] [1,2,4]TRIAZINE DERIVATIVE AND USE THEREOF FOR TREATING TUMORS Public/Granted day:2016-04-28
Information query
