Invention Grant
- Patent Title: Boron containing small molecules as antiprotozoal agents
- Patent Title (中): 含有小分子的硼作为抗原虫剂
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Application No.: US12852351Application Date: 2010-08-06
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Publication No.: US09440994B2Publication Date: 2016-09-13
- Inventor: Daitao Chen , Matthew Orr , Jessica Sligar , Robert Jacobs , Jacob J. Plattner
- Applicant: Daitao Chen , Matthew Orr , Jessica Sligar , Robert Jacobs , Jacob J. Plattner
- Applicant Address: US CA Palo Alto
- Assignee: Anacor Pharmaceuticals, Inc.
- Current Assignee: Anacor Pharmaceuticals, Inc.
- Current Assignee Address: US CA Palo Alto
- Agency: Morgan, Lewis & Bockius LLP
- Main IPC: C07F5/02
- IPC: C07F5/02

Abstract:
This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent. The exemplary compounds have the following formula: wherein X is selected from the group consisting of substituted phenyl, substituted or unsubstituted heteroaryl and unsubstituted cycloalkyl; R3a is selected from the group consisting of H, unsubstituted C1 or C2 or C3 or C4 or C5 or C6 alkyl and unsubstituted C3 or C4 or C5 or C6 cycloalkyl; R3b is selected from the group consisting of H, unsubstituted C1 or C2 or C3 or C4 or C5 or C6 alkyl and unsubstituted C3 or C4 or C5 or C6 cycloalkyl; with the proviso that R3a and R3b, along with the atom to which they are attached, are optionally joined to form a 3 or 4 or 5 or 6 membered ring, with the proviso that R3a and R3b cannot both be H, or a salt thereof.
Public/Granted literature
- US20110190235A1 BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS Public/Granted day:2011-08-04
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