A personal safety response system comprises a wearable device to be worn by a user, the wearable device includes a speaker configured for generating audio notification, an exterior visual indicator configured for generating visual notification, a vibrator configured for generating haptic notification, a panic button, a radio frequency transceiver, and a controller configured to recognize a first set of predetermined conditions, and transmit a notification to a base telephone. The base telephone includes a radio frequency transceiver configured for two-way communication with the wearable device, and transmit and receive data over the telecommunication network and Internet, a memory, a processor configured to recognize a second set of predetermined conditions, and transmit a notification to the wearable device, a user input device configured to receive user input, and a display screen configured to display information associated with the notification transmitted to the wearable device.