A current sense circuit having a single opamp DC offset auto-zero capability that allows for continuous current sensing operation while at the same time providing for DC offset sensing and compensation. The single opamp design can operate in a first phase to sense and store a DC offset, while providing an output to drive an output stage of the current sense circuit. The single opamp design can operate in a second phase, using the sensed DC offset to generate an accurate output that can drive the output stage and which can be used in the first phase.