Invention Grant
- Patent Title: Animal models and therapeutic molecules
- Patent Title (中): 动物模型和治疗分子
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Application No.: US13433084Application Date: 2012-03-28
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Publication No.: US09445581B2Publication Date: 2016-09-20
- Inventor: Allan Bradley , E-Chiang Lee , Qi Liang , Wei Wang , Dominik Spensberger , Hui Liu , Jasper Clube
- Applicant: Allan Bradley , E-Chiang Lee , Qi Liang , Wei Wang , Dominik Spensberger , Hui Liu , Jasper Clube
- Applicant Address: GB Cambridge
- Assignee: Kymab Limited
- Current Assignee: Kymab Limited
- Current Assignee Address: GB Cambridge
- Agency: Sunstein Kann Murphy & Timbers LLP
- Main IPC: C12P21/00
- IPC: C12P21/00 ; A01K67/027 ; C12N5/06 ; C12P21/08 ; C07K16/46 ; C12N15/85 ; C07K16/12 ; C07K16/18 ; C07K16/00

Abstract:
The invention discloses methods for the generation of chimaeric human—non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanized antibodies; compositions comprising the disclosed antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in the disclosed methods.
Public/Granted literature
- US20130263293A1 ANIMAL MODELS AND THERAPEUTIC MOLECULES Public/Granted day:2013-10-03
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