Invention Grant
US09445581B2 Animal models and therapeutic molecules 有权
动物模型和治疗分子

Animal models and therapeutic molecules
Abstract:
The invention discloses methods for the generation of chimaeric human—non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanized antibodies; compositions comprising the disclosed antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in the disclosed methods.
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