Invention Grant
US09445975B2 Composition and method for preparing stable unilamellar liposomal suspension
有权
制备稳定的单层脂质体悬浮液的组合物和方法
- Patent Title: Composition and method for preparing stable unilamellar liposomal suspension
- Patent Title (中): 制备稳定的单层脂质体悬浮液的组合物和方法
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Application No.: US12245528Application Date: 2008-10-03
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Publication No.: US09445975B2Publication Date: 2016-09-20
- Inventor: Penelope M. Anderson
- Applicant: Penelope M. Anderson
- Applicant Address: US MI Ada
- Assignee: ACCESS BUSINESS GROUP INTERNATIONAL, LLC
- Current Assignee: ACCESS BUSINESS GROUP INTERNATIONAL, LLC
- Current Assignee Address: US MI Ada
- Agency: Brinks Gilson & Lione
- Agent G. Peter Nichols
- Main IPC: A61K9/127
- IPC: A61K9/127 ; A61K8/14 ; A61K8/34 ; A61K8/55 ; A61K8/63 ; A61K8/67 ; A61K8/68 ; A61K9/00 ; A61K9/06 ; A61Q19/00 ; A61Q19/08 ; B82Y5/00

Abstract:
Compositions and methods for producing and using stable transparent to translucent unilamellar liposomal suspensions are described. The suspensions include a liposome preparation having a uniform plurality of unilamellar liposomal particles with a mean particle size between about 50 nm to about 290 nm. The particles are suspended in an external phase composition that has a density between about 0.95 g/cc and about 1.25 g/cc, and that is present in an amount between about 30% to about 75% of the weight of the liposomal suspension. The liposome preparation is formed from an aqueous liposomal solution that includes an oil-soluble composition and a water-soluble composition. The oil-soluble composition is present at a concentration between about 5% to about 33% by weight of the liposomal solution and the water-soluble composition is present at a concentration between about 67% to about 95% by weight of the liposomal solution.
Public/Granted literature
- US20100086573A1 COMPOSITION AND METHOD FOR PREPARING STABLE UNILAMELLAR LIPOSOMAL SUSPENSION Public/Granted day:2010-04-08
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