Invention Grant
- Patent Title: Compositions and methods for neovascularization
- Patent Title (中): 新血管形成的组成和方法
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Application No.: US13743223Application Date: 2013-01-16
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Publication No.: US09446031B2Publication Date: 2016-09-20
- Inventor: Michael Raghunath , Sei Hien Lim , Roger Dale Kamm
- Applicant: National University of Singapore , Massachusetts Institute of Technology
- Applicant Address: SG Singapore US MA Cambridge
- Assignee: National University of Singapore,Massachusetts Institute of Technology
- Current Assignee: National University of Singapore,Massachusetts Institute of Technology
- Current Assignee Address: SG Singapore US MA Cambridge
- Agency: Hamilton, Brook, Smith & Reynolds, P.C.
- Main IPC: A01N43/40
- IPC: A01N43/40 ; A61K31/44 ; A01N43/00 ; A61K31/397 ; A61K31/4412 ; C12N5/07 ; A61K31/688 ; C12N5/071
Abstract:
The invention is directed to a method of inducing angiogenesis at a site in an individual in need thereof comprising administering locally to the site an effective amount of one or more agents that induce hypoxia induced factor 1α (HIF-1α). In another aspect, the invention is directed to a method of inducing angiogenesis at a site in an individual in need thereof comprising administering locally to the site an effective amount of one or more agents that induce hypoxia induced factor 1α (HIF-1α) and one or more lysophospholipids. In addition, the invention is directed to methods of generating prevascularized tissue, methods of generating a vascular network in a device and compositions thereof.
Public/Granted literature
- US20130197038A1 Compositions And Methods For Neovascularization Public/Granted day:2013-08-01
Information query
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