Invention Grant
US09446053B2 Method for enhancing the secretion of GLP-1 using bitter compounds
有权
用苦味化合物增强GLP-1分泌的方法
- Patent Title: Method for enhancing the secretion of GLP-1 using bitter compounds
- Patent Title (中): 用苦味化合物增强GLP-1分泌的方法
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Application No.: US13855108Application Date: 2013-04-02
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Publication No.: US09446053B2Publication Date: 2016-09-20
- Inventor: Ching-jang Huang , Yi-ping Pai , Ting-ni Huang
- Applicant: National Taiwan University
- Applicant Address: TW Taipei
- Assignee: National Taiwan University
- Current Assignee: National Taiwan University
- Current Assignee Address: TW Taipei
- Agency: WPAT, P.C., Intellectual Property Attorneys
- Agent Anthony King
- Priority: TW102105095A 20130208
- Main IPC: A61K31/58
- IPC: A61K31/58 ; A61K31/26 ; A61K31/575
Abstract:
The present invention provides a method for enhancing the secretion of GLP-1 of the intestinal endocrine L-cells using a bitter compound, wherein the bitter compound is a cucurbitane-triterpenoid or allyl isothiocyanate. The bitter compound can regulate the secretion of GLP-1, thus is potentially reliable for the development of medicament or healthy victual.
Public/Granted literature
- US20140228332A1 METHOD FOR ENHANCING THE SECRETION OF GLP-1 USING BITTER COMPOUNDS Public/Granted day:2014-08-14
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