Invention Grant
- Patent Title: BTK inhibitors
- Patent Title (中): BTK抑制剂
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Application No.: US14762929Application Date: 2014-01-17
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Publication No.: US09446130B2Publication Date: 2016-09-20
- Inventor: Ronald M. Kim , Jian Liu , Hao Wu , Shilan Liu , Chundao Yang , Shuling Zheng
- Applicant: MERCK SHARP & DOHME CORP.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Matthew A. Leff; John C. Todaro
- Priority: WOPCT/CN2013/070898 20130123
- International Application: PCT/US2014/011950 WO 20140117
- International Announcement: WO2014/116504 WO 20140731
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D473/34 ; A61K31/519 ; A61K31/4985 ; A61P19/02 ; A61K45/06 ; C07D519/00

Abstract:
The present invention provides Bruton's Tyrosine Kinase (Btk) inhibitor compounds according to Formula I or pharmaceutically acceptable salts thereof. Formula I or a pharmaceutically acceptable salt thereof or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of Btk inhibitor compounds in the treatment of Btk mediated disorders.
Public/Granted literature
- US20150353565A1 BTK INHIBITORS Public/Granted day:2015-12-10
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