Invention Grant
US09446152B2 Polyethylene glycol based oligomers for coating nanoparticles, nanoparticles coated therewith, and related methods
有权
用于涂覆纳米颗粒的聚乙二醇基低聚物，用其涂覆的纳米颗粒及相关方法
- Patent Title: Polyethylene glycol based oligomers for coating nanoparticles, nanoparticles coated therewith, and related methods
- Patent Title (中): 用于涂覆纳米颗粒的聚乙二醇基低聚物，用其涂覆的纳米颗粒及相关方法
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Application No.: US14838586Application Date: 2015-08-28
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Publication No.: US09446152B2Publication Date: 2016-09-20
- Inventor: Hedi Mattoussi , Goutam Palui , Hyon Bin Na
- Applicant: The Florida State University Research Foundation, Inc.
- Applicant Address: US FL Tallahassee
- Assignee: The Florida State University Research Foundation, Inc.
- Current Assignee: The Florida State University Research Foundation, Inc.
- Current Assignee Address: US FL Tallahassee
- Agency: Armstrong Teasdale LLP
- Main IPC: A61K49/00
- IPC: A61K49/00 ; H01F1/00 ; C08F8/32 ; C08F20/06 ; C08F22/00 ; C08K5/00 ; C08K5/13 ; C08L33/00 ; C08L71/08 ; C09D133/14 ; C08F220/26
Abstract:
In a composition aspect of the invention, a nanoparticle coating comprises repeating polyacrylic acid monomers covalently bound together in an aliphatic chain having a plurality of carboxylic acid functional groups and modified carboxylic acid functional groups extending therefrom. A first portion of the modified carboxylic acid functional groups are modified by a PEG oligomer having a terminal methoxy functional group and a second portion of the modified carboxylic acid functional groups are modified by a PEG oligomer having at least one terminal sulfur moiety.
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