Invention Grant
- Patent Title: Gas-filled microvesicles with polymer-modified lipids
- Patent Title (中): 具有聚合物改性脂质的充气微泡
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Application No.: US12440009Application Date: 2007-09-04
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Publication No.: US09446156B2Publication Date: 2016-09-20
- Inventor: Stephane Gorgerat , Christian Guillot , Feng Yan
- Applicant: Stephane Gorgerat , Christian Guillot , Feng Yan
- Applicant Address: CH Manno
- Assignee: BRACCO SUISSE S.A.
- Current Assignee: BRACCO SUISSE S.A.
- Current Assignee Address: CH Manno
- Agency: Vivicar Law, PLLC
- Priority: EP06120109 20060905
- International Application: PCT/EP2007/059256 WO 20070904
- International Announcement: WO2008/028917 WO 20080313
- Main IPC: A61K49/22
- IPC: A61K49/22 ; A61K49/18 ; A61K51/12
Abstract:
Image enhancing contrast agents for use in diagnostic and/or therapeutic methods, particularly in the form of gas-filled microvesicles, with enhanced stability. The gas-filled microvesicles are stabilized by a layer of amphiphilic material and comprise from 0.15% to 1.0% by moles of a lipid bearing a hydrophilic polymer. The lipid bearing a hydrophilic polymer is preferably a phospholipid linked to polyethyleneglycol.
Public/Granted literature
- US20090263330A1 GAS-FILLED MICROVESICLES WITH POLYMER-MODIFIED LIPIDS Public/Granted day:2009-10-22
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