Invention Grant
US09446166B2 Fibrin sealant compositions with chemical crosslinking 有权
具有化学交联的纤维蛋白密封剂组合物

  • Patent Title: Fibrin sealant compositions with chemical crosslinking
  • Patent Title (中): 具有化学交联的纤维蛋白密封剂组合物
  • Application No.: US13748678
    Application Date: 2013-01-24
  • Publication No.: US09446166B2
    Publication Date: 2016-09-20
  • Inventor: Chetan Anirudh Khatri
  • Applicant: ETHICON, INC.
  • Applicant Address: US NJ Somerville
  • Assignee: Ethicon, Inc.
  • Current Assignee: Ethicon, Inc.
  • Current Assignee Address: US NJ Somerville
  • Agent David R. Crichton; Leo B. Kriksunov
  • Main IPC: A61K31/74
  • IPC: A61K31/74 A61L24/00
Fibrin sealant compositions with chemical crosslinking
Abstract:
The invention relates to tissue adhesives or sealants, more specifically to fibrinogen based sealants reinforced with particulate material and chemically cross-linked. More particularly, the present invention is directed to tissue sealant, adhesive, hemostat, or scaffolding material containing thrombin, fibrinogen, a biocompatible particulate material having amine functionality, and a biocompatible polymer containing aldehyde groups. The present invention is also directed to methods for the use of such materials.
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