Invention Grant
- Patent Title: Inhibitors of protein phosphatase-1 and uses thereof
- Patent Title (中): 蛋白磷酸酶-1抑制剂及其用途
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Application No.: US14421757Application Date: 2013-03-14
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Publication No.: US09447047B2Publication Date: 2016-09-20
- Inventor: Sergei Nekhai , Alexander Bukreyev
- Applicant: Sergei Nekhai , Alexander Bukreyev
- Applicant Address: US DC Washington US TX Austin
- Assignee: Howard University,The Board of Regents of the University of Texas System
- Current Assignee: Howard University,The Board of Regents of the University of Texas System
- Current Assignee Address: US DC Washington US TX Austin
- Agency: Fitch, Even, Tabin & Flannery LLP
- International Application: PCT/US2013/031659 WO 20130314
- International Announcement: WO2014/028051 WO 20140220
- Main IPC: A61K31/47
- IPC: A61K31/47 ; C07D219/04 ; A61K31/473 ; C07D221/16 ; C07D409/06 ; C07D417/12

Abstract:
Inhibitors of protein phosphatase-1 (PP-1) and their use in a method for the treatment or prevention of viral infections caused by HIV or ebola virus are disclosed. Inhibitors of protein phosphatase-1 in effective amounts have been shown to slow down viral replication upon contacting ebola virus or cells containing the ebola virus.
Public/Granted literature
- US20160024013A1 Inhibitors of Protein Phosphatase-1 and Uses Thereof Public/Granted day:2016-01-28
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