Invention Grant
- Patent Title: Process for the preparation of calcobutrol
- Patent Title (中): 制备钙调蛋白的方法
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Application No.: US13508198Application Date: 2010-11-02
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Publication No.: US09447053B2Publication Date: 2016-09-20
- Inventor: Johannes Platzek , Wilhelm Trentmann
- Applicant: Johannes Platzek , Wilhelm Trentmann
- Applicant Address: DE Monheim
- Assignee: Bayer Intellectual Property GMBH
- Current Assignee: Bayer Intellectual Property GMBH
- Current Assignee Address: DE Monheim
- Agent Joseph L. Kent; David Schramm; James R. Stevenson
- Priority: DE102009053171 20091104
- International Application: PCT/EP2010/066655 WO 20101102
- International Announcement: WO2011/054827 WO 20110512
- Main IPC: C07D257/02
- IPC: C07D257/02
Abstract:
A process for the preparation of the calcium complex of 10-(2, 3-Dihydroxy-1-(hydroxymethyl)propyl)-1,4,7,10-tetraazacyclodecane-4,7-triacetic acid, also known as Calcobutrol, starting from the pure gadolinium complex (Gadobutrol) is disclosed. Also disclosed is Calcobutrol with a hitherto unknown level of purity.
Public/Granted literature
- US20120309962A1 PROCESS FOR THE PREPARATION OF CALCOBUTROL Public/Granted day:2012-12-06
Information query
