Invention Grant
- Patent Title: Schiff bases of thiazoles: a new class of ureases inhibitors
- Patent Title (中): 噻唑的席夫碱：一类新的脲酶抑制剂
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Application No.: US14310738Application Date: 2014-06-20
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Publication No.: US09447057B2Publication Date: 2016-09-20
- Inventor: Muhammad Iqbal Choudhary , Ajmal Khan , Khalid M. Khan , Nida Ambreen , Atia-tul Wahab , Atta-ur Rahman
- Applicant: Muhammad Iqbal Choudhary , Ajmal Khan , Khalid M. Khan , Nida Ambreen , Atia-tul Wahab , Atta-ur Rahman
- Agent Sarfaraz K. Niazi
- Main IPC: A61K31/40
- IPC: A61K31/40 ; A61K31/44 ; C07D277/42 ; C07D417/12 ; C07D401/12 ; A61K31/427 ; A61K31/4439
Abstract:
One embodiment of the invention relates to treating diseases associated with increased urease enzyme activity comprising administering an effective amount of a compound selected from a group consisting of 28 thiazoles Schiff bases. Kinetic studies were performed on ten (10) of the most active compounds.
Public/Granted literature
- US20150368214A1 SCHIFF BASES OF THIAZOLES: A NEW CLASS OF UREASES INHIBITORS Public/Granted day:2015-12-24
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