Invention Grant
- Patent Title: Pyridazine derivatives as EAAT2 activators
- Patent Title (中): 哒嗪衍生物作为EAAT2激活剂
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Application No.: US14236041Application Date: 2012-08-02
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Publication No.: US09447075B2Publication Date: 2016-09-20
- Inventor: Gregory D. Cuny , Marcie Glicksman , Xeuchao Xing , Chien-Liang Glenn Lin
- Applicant: Gregory D. Cuny , Marcie Glicksman , Xeuchao Xing , Chien-Liang Glenn Lin
- Applicant Address: US MA Boston US OH Columbus
- Assignee: The Brigham and Women's Hospital, Inc.,The Ohio State University
- Current Assignee: The Brigham and Women's Hospital, Inc.,The Ohio State University
- Current Assignee Address: US MA Boston US OH Columbus
- Agency: Fish & Richardson P.C.
- International Application: PCT/US2012/049311 WO 20120802
- International Announcement: WO2013/019938 WO 20130207
- Main IPC: A61K31/50
- IPC: A61K31/50 ; A61K31/501 ; C07D401/14 ; C07D401/04 ; C07D237/18 ; C07D213/32
Abstract:
Pyridazine derivatives that activate the excitatory amino acid transporter 2 (EAAT2), and methods use thereof for treating or preventing diseases, disorders, and conditions associated with glutamate excitotoxicity.
Public/Granted literature
- US20140303174A1 Pyridazine derivatives as EAAT2 Activators Public/Granted day:2014-10-09
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