Invention Grant
US09447087B2 Galactokinase inhibitors for the treatment and prevention of associated diseases and disorders
有权
用于治疗和预防相关疾病和障碍的半乳糖激酶抑制剂
- Patent Title: Galactokinase inhibitors for the treatment and prevention of associated diseases and disorders
- Patent Title (中): 用于治疗和预防相关疾病和障碍的半乳糖激酶抑制剂
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Application No.: US14346400Application Date: 2011-09-23
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Publication No.: US09447087B2Publication Date: 2016-09-20
- Inventor: Matthew B. Boxer , Martin J. Walsh , Li Liu , Cordelle D. Tanega , Min Shen , Kent Lai , Manshu Tang , Douglas S. Auld
- Applicant: Matthew B. Boxer , Martin J. Walsh , Li Liu , Cordelle D. Tanega , Min Shen , Kent Lai , Manshu Tang , Douglas S. Auld
- Applicant Address: US UT Salt Lake City
- Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION
- Current Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION
- Current Assignee Address: US UT Salt Lake City
- Agency: Stoel Rives LLP
- International Application: PCT/US2011/053021 WO 20110923
- International Announcement: WO2013/043192 WO 20130328
- Main IPC: C07D403/12
- IPC: C07D403/12 ; A61K31/506 ; C07D417/14 ; C07D413/14 ; C07D413/12 ; C07D493/10 ; C07D495/10 ; C07D491/107
Abstract:
Disclosed are inhibitors of human galactokinase of formula (1) that are useful in treating or preventing a galactokinase mediated disease or disorder, e.g., galactosemia. Also disclosed are a composition comprising a pharmaceutically acceptable carrier and at least one inhibitor of the invention, and a method of treating or preventing such disease or disorder in a mammal. Formula (I).
Public/Granted literature
- US20140288100A1 GALACTOKINASE INHIBITORS FOR THE TREATMENT AND PREVENTION OF ASSOCIATED DISEASES AND DISORDERS Public/Granted day:2014-09-25
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