Invention Grant
- Patent Title: Imidazopyridine compounds
- Patent Title (中): 咪唑并吡啶化合物
-
Application No.: US14090074Application Date: 2013-11-26
-
Publication No.: US09447090B2Publication Date: 2016-09-20
- Inventor: Yuji Koga , Kyoichi Maeno , Ippei Sato , Yoshimasa Imamura , Takeshi Hanazawa , Maiko Iida , Kazuhiko Ohne , Kenichiro Imamura , Tsubasa Watanabe , Eisuke Nozawa , Hiroshi Shibata
- Applicant: Astellas Pharma Inc.
- Applicant Address: JP Tokyo
- Assignee: Astellas Pharma Inc.
- Current Assignee: Astellas Pharma Inc.
- Current Assignee Address: JP Tokyo
- Agent Amy H. Fix
- Priority: JP2011-119826 20110530; JP2011-287682 20111228
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D453/02 ; C07D519/00

Abstract:
An excellent drug for treating or preventing cardiovascular diseases, based on cGMP production enhancing action due to soluble guanylate cyclase activating action, is provided. It was found that imidazopyridine compounds having a carbamoyl group at the 3-position and a substituent bonded at the 8-position via an oxygen atom in an imidazo[1,2-a]pyridine skeleton exhibits a cGMP production enhancing action by a potent soluble guanylate cyclase activating action, and is useful as a drug for treating or preventing various soluble guanylate cyclase-related cardiovascular diseases, thereby completing the present invention.
Public/Granted literature
- US20140088080A1 IMIDAZOPYRIDINE COMPOUNDS Public/Granted day:2014-03-27
Information query