Invention Grant
US09447095B2 Pyrimidine derivatives as phosphodiesterase 10 inhibitors (PDE-10)
有权
嘧啶衍生物作为磷酸二酯酶10抑制剂（PDE-10）
- Patent Title: Pyrimidine derivatives as phosphodiesterase 10 inhibitors (PDE-10)
- Patent Title (中): 嘧啶衍生物作为磷酸二酯酶10抑制剂（PDE-10）
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Application No.: US14762655Application Date: 2014-01-24
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Publication No.: US09447095B2Publication Date: 2016-09-20
- Inventor: Juan Camacho Gómez , Julio Castro Palomino Laria
- Applicant: PALOBIOFARMA S.L.
- Applicant Address: ES Barcelona
- Assignee: PALOBIOFARMA S.L.
- Current Assignee: PALOBIOFARMA S.L.
- Current Assignee Address: ES Barcelona
- Agency: Moore & Van Allen, PLLC
- Agent Tristan A. Fuierer
- Priority: ES201330082 20130124
- International Application: PCT/EP2014/051290 WO 20140124
- International Announcement: WO2014/114695 WO 20140731
- Main IPC: C07D403/04
- IPC: C07D403/04 ; A61K31/506 ; C07D471/04 ; C07D417/14 ; C07D405/14 ; A61K31/5377 ; A61K45/06 ; C07D401/14
Abstract:
The present invention relates to novel pyrimidine derivatives of formula (I) as inhibitors of the enzyme phosphodiesterase 10 (PDE-10), pharmaceutical compositions comprising an effective amount of these compounds and the use of the compounds for manufacturing a medicament for the treatment of pathological conditions or diseases that can improve by inhibition of the enzyme Phosphodiesterase 10 such as neurological, psychiatric, respiratory or metabolic diseases.
Public/Granted literature
- US20150336953A1 NEW PYRIMIDINE DERIVATIVES AS PHOSPHODIESTERASE 10 INHIBITORS (PDE-10) Public/Granted day:2015-11-26
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