Invention Grant
US09447154B2 Nucleic acids encoding a house dust mite allergen, Der p III, and uses thereof
有权
编码房尘螨过敏原的核酸，Der p III及其用途
- Patent Title: Nucleic acids encoding a house dust mite allergen, Der p III, and uses thereof
- Patent Title (中): 编码房尘螨过敏原的核酸，Der p III及其用途
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Application No.: US12358954Application Date: 2009-01-23
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Publication No.: US09447154B2Publication Date: 2016-09-20
- Inventor: Wayne R. Thomas , Kaw-Yan Chua , Bruce L. Rogers , Mei-chang Kuo
- Applicant: Wayne R. Thomas , Kaw-Yan Chua , Bruce L. Rogers , Mei-chang Kuo
- Applicant Address: DE Darmstadt
- Assignee: MERCK PATENT GMBH
- Current Assignee: MERCK PATENT GMBH
- Current Assignee Address: DE Darmstadt
- Agent Ronald J. Kamis
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/395 ; C07K16/00 ; C12P21/08 ; C07K14/435 ; A61K38/00
Abstract:
Isolated nucleic acids encoding an allergen of Dermatophagoides pteronyssinus, Der p III, are disclosed. A cDNA encoding a peptide having a Der p III activity and a predicted molecular weight of about 24,985 daltons is also described. The nucleic acids can be used as probes to detect the presence of Der p III nucleic acid in a sample or for the recombinant production of peptides having an activity of Der p III. Peptides having an activity of Der p III can be used in compositions suitable for pharmaceutical administration or methods of diagnosing sensitivity to house dust mites.
Public/Granted literature
- US20110059522A1 NUCLEIC ACIDS ENCODING A HOUSE DUST MITE ALLERGEN, DER P III, AND USES THEREOF Public/Granted day:2011-03-10
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