Invention Grant
- Patent Title: Human antibodies to respiratory syncytial virus F protein and methods of use thereof
- Patent Title (中): 呼吸道合胞病毒F蛋白的人抗体及其使用方法
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Application No.: US14207797Application Date: 2014-03-13
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Publication No.: US09447173B2Publication Date: 2016-09-20
- Inventor: Anne Gurnett-Bander , David Perez-Caballero , Sumathi Sivapalasingam , Xunbao Duan , Douglas MacDonald
- Applicant: Regeneron Pharmaceuticals, Inc.
- Applicant Address: US NY Tarrytown
- Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee Address: US NY Tarrytown
- Agency: Alston & Bird LLP
- Agent Veronica Mallon
- Main IPC: C07K16/10
- IPC: C07K16/10 ; A61K39/42 ; A61K39/155 ; A61K45/06 ; G01N33/569
Abstract:
The present invention provides fully human antibodies that bind to respiratory syncytial virus F protein, compositions comprising the antibodies and methods of use. The antibodies of the invention are useful for preventing fusion of the virus with the cell membrane and preventing cell to cell spread of the virus, thereby providing a means of preventing the infection, or treating a patient suffering from the infection and ameliorating one or more symptoms or complications associated with the viral infection. The antibodies may also be useful for diagnosis of an infection by RSV.
Public/Granted literature
- US20140271653A1 HUMAN ANTIBODIES TO RESPIRATORY SYNCYTIAL VIRUS F PROTEIN AND METHODS OF USE THEREOF Public/Granted day:2014-09-18
Information query
