Invention Grant
- Patent Title: Transgenic mouse homozygous for chimeric IgH locus
- Patent Title (中): 用于嵌合IgH基因座的转基因小鼠是纯合的
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Application No.: US13416684Application Date: 2012-03-09
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Publication No.: US09447177B2Publication Date: 2016-09-20
- Inventor: Allan Bradley , E-Chiang Lee , Qi Liang , Wei Wang , Glenn Friedrich
- Applicant: Allan Bradley , E-Chiang Lee , Qi Liang , Wei Wang , Glenn Friedrich
- Applicant Address: GB Cambridge
- Assignee: Kymab Limited
- Current Assignee: Kymab Limited
- Current Assignee Address: GB Cambridge
- Agency: Sunstein Kann Murphy & Timbers LLP
- Priority: GB0911846.4 20090708; GB0913102.0 20090728
- Main IPC: A01K67/027
- IPC: A01K67/027 ; C07K16/00 ; C12N15/85 ; C07K16/18 ; C07K16/12 ; C07K16/46 ; A61K39/02 ; A61K39/35
Abstract:
The invention discloses methods for the generation of chimaeric human—non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanized antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.
Public/Granted literature
- US09290566B2 Transgenic mouse homozygous for chimeric IgH locus Public/Granted day:2016-03-22
Information query
