Invention Grant
- Patent Title: Method for producing 3-acetylamino-4-hydroxybenzoic acid
- Patent Title (中): 3-乙酰氨基-4-羟基苯甲酸的制备方法
-
Application No.: US14547481Application Date: 2014-11-19
-
Publication No.: US09447443B2Publication Date: 2016-09-20
- Inventor: Fumi Shozui , Yoshinori Tajima , Keiichi Yokoyama
- Applicant: AJINOMOTO CO., INC.
- Applicant Address: JP Tokyo
- Assignee: AJINOMOTO CO., INC.
- Current Assignee: AJINOMOTO CO., INC.
- Current Assignee Address: JP Tokyo
- Agency: Cermak Nakajima & McGowan LLP
- Agent Shelly Guest Cermak
- Priority: JP2012-122388 20120529
- Main IPC: C12P13/02
- IPC: C12P13/02 ; C12P7/22 ; C12P7/42 ; C12N9/10 ; C12P13/00 ; C08G73/22

Abstract:
The present invention provides a method for conveniently and efficiently producing a 3-acetylamino-4-hydroxybenzoic acid-type compound that is a stable compound by a process using a microorganism. Specifically the present invention provides a microorganism having an ability to produce 3-amino-4-hydroxybenzoic acid, that is modified so as to increase an activity to form 3-amino-4-hydroxybenzoic acid from dihydroxyacetone phosphate and aspartate semialdehyde, wherein the microorganism is modified so as to increase an N-hydroxyarylamine O-acetyltransferase (NhoA) activity, as well as a method for producing the 3-acetylamino-4-hydroxybenzoic acid-type compound using such a microorganism.
Public/Granted literature
- US20150079644A1 Method for Producing 3-Acetylamino-4-Hydroxybenzoic Acid Public/Granted day:2015-03-19
Information query